Textbook Pathology Outlines: Stains CDX2

Currently in progress, available in 09/2020

Definition:
Homeobox gene that encodes a nuclear transcription factor critical for intestinal embryonic development; relatively specific for intestinal epithelium (but see positive staining below)
Terminology:
Also called caudal-related homeobox gene 2, caudal type homeobox transcription factor 2
Homologue of Drosophila melanogaster homeobox gene-caudal

More articles

Textbook Pathology Outlines: Colon Tumor Polyps General

Erem, AS, Van Treeck, BJ, Hartley, C.

Definition / general
A polyp is an exophytic or sessile lesion distinct from the mucosal surface and may be neoplastic or nonneoplastic
Essential features
> 95% of colorectal adenocarcinoma arises from polyps
Usually asymptomatic

A Rare Case of Multiple Primary Lung Cancers in a Single Patient

Erem, A.S., Cecchini M. J., Boland, J.M.

This is an exciting project that is supervised by Mayo Clinic, Rochester, and Western University, Ontario.

In this study, we will detail a case of Multiple Primary Lung Cancers in one female patient.
One of the more difficult aspects when evaluating a patient's tumor staging, prognosis, and treatment strategy is whether metastasis has occurred, a diagnosis made all the more difficult when MPLC are suspected.